Chuck Caldwell was in Europe with his wife in September 2015 when his
throat started bothering him. At the time, he chalked up the soreness
to allergies or drainage and didn’t give it much thought.
But when Chuck got back to Houston later that year, he started
feeling lightheaded, and the pain in his throat began radiating up
into his ear. A few days before Christmas, Chuck finally saw his
doctor, who used a scope to examine him.
The news was not good. “I asked him if it was throat cancer, and he was almost positive it
was,” Chuck says. “But he also thought it was fixable, and said he was
going to refer me to the No. 1 guy in the U.S.: his brother.”
Choosing a clinical trial to help others
“That guy” turned out to be MD
Anderson’s Randal Weber, M.D., and Chuck got an appointment
with him during the first week of 2016.
Weber confirmed the throat cancer diagnosis and recommended a
treatment plan of radiation and chemotherapy. G. Brandon Gunn, M.D., Chuck’s radiation
oncologist, asked if he would consider a proton therapy clinical trial. The 77-year-old
“It sounds kind of Pollyanna, but if it will help someone else down
the line, I would always do it,” Chuck says. “It’s worth it and a
small price to pay.”
A risk that paid off
Chuck’s only real concern was the possibility of not receiving proton therapy. As a clinical trial participant,
Chuck knew that a computer would randomly determine whether he’d
receive standard radiation or proton therapy, and he really wanted the latter.
“My wife and I both work, and if I’d gotten regular radiation, I
would have had to go between 8 a.m. and 5 p.m., which is a hardship,”
Chuck says. “But the MD Anderson Proton Therapy
Center is open around the clock, so we could go there
between 8 and 11 p.m. Also, MD Anderson is
one of only about 24 places in the U.S. that offer proton therapy, and
it’s the only one in Houston. This clinical trial wouldn’t have been
an option anywhere else close by.”
As it turns out, the computer placed Chuck in the proton therapy
group. On Feb. 8, he began receiving proton therapy five days a week
under Gunn and chemotherapy once a week under Merrill Kies, M.D. He rang the gong in the
Proton Therapy Center to mark the end of his treatment on March 29,
and has shown no evidence of disease since then.
“Everything worked out super,” Chuck says.
Side effect has unintended benefit
For Chuck, the most discouraging part of his cancer experience has
been losing his sense of taste. That happened 15 days into his
treatment, and it still hasn’t returned.
“I’m not much of a pie and cake person, but I can eat my weight in
ice cream,” Chuck says. “Now, rocky road tastes like mud. Going
through cancer treatment isn’t much fun, but if you had something to
look forward to, like a meal, it wouldn’t be so bad. It gets to where
you just don’t want to eat.”
Not being able to taste anything has had one unexpected benefit:
since starting treatment, Chuck has dropped almost 60 pounds.
“I needed to lose weight, but that was kind of a hard way to do it,”
Chuck says. “I think I was born weighing 125. Now I’m wearing clothes
I haven’t worn in 30 years. And I can breathe much more easily.”
Staying positive and spreading the word
Today, Chuck considers himself fortunate.
“My sense of taste is still coming back gradually, and the doctor
said it could take up to a year,” Chuck says. “But I’m OK with that.
During treatment, every time I started feeling sorry for myself, I’d
walk around the hospital and see babies with no hair or people with
half a face. That brought everything back into focus. There was an end
to my ordeal, and the odds were really good that I was going to get well.”
He also remains one of MD Anderson’s
“I don’t understand why anyone with a cancer diagnosis would go
anywhere but MD Anderson,” Chuck says. “It
would be hard for anybody to compete with this operation. The doctors
are superb. The nurses are outstanding, and they have more clinical
trials than anyone else. Everybody there makes you feel like you’re
their only patient.”