Researchers from the Boston University School of Medicine (BUSM) have determined how the TGFβ-Smad signaling pathway, which is over activated in late-stage cancers, is responsible for the "epigenetic memory" that maintains unique patterns of regulatory DNA hypermethylation causing silencing of criti

Researchers at Dana-Farber Cancer Institute have discovered a gene activity signature that predicts a high risk of cancer recurrence in certain breast tumors that have been treated with commonly used chemotherapy drugs. Despite their resistance to drugs of the anthracycline class, the breast cancer

A large New York medical center reduced the number of CT scans and radiation dose delivered to emergency department patients with suspected pulmonary emboli (PE) by holding collaborative educational seminars for staff and routing patients to CT pulmonary angiography (CTPA) or ventilation perfusion (

Data from one of the largest mammography trials in history demonstrates that overall the radiation dose associated with digital mammography is significantly lower (averaging 22 percent lower) than that of conventional film mammography and that the reduction could be greater in women with larger and

A study by researchers at Tufts University School of Medicine, the Sackler School of Graduate Biomedical Sciences at Tufts, and Tufts Medical Center improves our current understanding of the origins of breast cancer. The researchers propose a new model for breast cell differentiation that identifies

Over 60 per cent of women who have a form of breast cancer in the milk ducts (DCIS*) are spared a mastectomy, according to latest research published today in the British Journal of Cancer. Researchers for the Sloane Project** examined how the size of the DCIS - measured by both imaging and patholog

Cancer Research UK scientists have shown for the first time how preventing two receptors - 'cell antennae' - communicating with each other can influence the activity of oestrogen, the hormone that fuels the progression of breast cancer in many women. The research is published in Genes and Developmen

A significant percentage of U.S. women 70 years or older who were severely cognitively impaired received screening mammography that was unlikely to benefit them, according to a study of 2,131 elderly women conducted by researchers from the University of California, San Francisco. Overall, 18 percen

A genetic mutation can significantly increases a woman's risk of developing breast cancer and ovarian cancer. But does that mean everyone should be tested? A new direct-to-consumer advertising campaign in select markets nationwide urges women to get tested. But experts from the University of Michig

2010 marks the 10th anniversary of the only international conference dedicated to the critical issues of young breast cancer survivors and those who care about them. Nearly 1,000 young breast cancer survivors, caregivers and medical professionals from around the world are expected to attend the 10th